BACKGROUND: Stage 1 hypertension influences acute cardiovascular responses to resistance exercises and post-exercise recovery. We examined whether the order of exercises, particularly in agonist-antagonist pairings, can alter these cardiovascular responses. This study compares systolic and diastolic blood pressure responses during agonist and agonist-antagonist paired sets of upper and lower-body resistance exercises with a load of 75% repetition maximum in individuals with normotension and stage 1 hypertension. METHODS: A cross-sectional study enrolled 47 participants with sedentary jobs, comprising 30 normotensive individuals (47.8 ± 5.9 years, height 174.8 ± 10.2 cm, weight 77.7 ± 15.4 kg, BMI 25.3 ± 3.6 kg/m2) and 17 hypertensive individuals (54.3 ± 6.0 years, 177.6 ± 11.3 cm, 89.8 ± 16.4 kg, BMI 28.5 ± 4,5 kg/m2). Acute cardiovascular parameters were measured using an arteriograph, a non-invasive device designed to assess vascular stiffness and cardiovascular health, after each set of resistance training. RESULTS: No significant differences in systolic blood pressure changes were found between the resistance training methods and aerobic exercise when comparing normotensive and hypertensive individuals. However, significant increases in systolic blood pressure were observed during lower-body exercises (11.3-24.7 mmHg for normotensives and 11.7-24.1 mmHg for hypertensives, p < 0.05). Hypertensive individuals showed slightly higher increases during lower-body supersets (p < 0.05). Regarding diastolic blood pressure, significant decreases were noted during upper-body resistance training for both groups, especially for normotensives (-10.6 to -13.7 mmHg, p < 0.05). CONCLUSIONS: Agonist and agonist-antagonist paired set resistance training for both lower and upper-body exercises resulted in similar blood pressure changes in individuals with normotension and stage 1 hypertension. These findings suggest that both methods may have comparable cardiovascular effects across blood pressure. TRIAL REGISTRATION: The study was registered on ClinicalTrials.gov (NCT06047678). Registration date: 31 August 2023.

Faculty of Physical Education and Sport Charles University José Martího 269 31 Prague 162 52 Czech Republic

The Jerzy Kukuczka Academy of Physical Education and Sport in Katowice Mikołowska 72A Katowice 40 065 Poland

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Grgic J, et al. Effects of resistance training performed to repetition failure or non-failure on muscular strength and hypertrophy: A systematic review and meta-analysis. J Sport Health Sci. 2022;11(2):202–11. PubMed PMC

Fyfe JJ, Hamilton DL, Daly RM. Minimal-dose resistance training for improving muscle mass, strength, and function: a narrative review of current evidence and practical considerations. Sports Med. 2022;52(3):463–79. PubMed

Palermi S, et al. Athlete’s heart: a cardiovascular step-by-step multimodality approach. Rev Cardiovasc Med. 2023;24(5). PubMed PMC

Martinez MW, et al. Exercise-induced cardiovascular adaptations and approach to exercise and cardiovascular disease: JACC state-of-the-art review. J Am Coll Cardiol. 2021;78(14):1453–70. PubMed

Mitchell J, et al. The role of muscle mass in the cardiovascular response to static contractions. J Physiol. 1980;309(1):45–54. PubMed PMC

Lind A, McNicol G. Muscular factors which determine the cardiovascular responses to sustained and rhythmic exercise. Can Med Assoc J. 1967;96(12):706. PubMed PMC

Mitchell JH. Abnormal cardiovascular response to exercise in hypertension: contribution of neural factors. Am J Physiology-Regulatory Integr Comp Physiol. 2017;312(6):R851–63. PubMed

de Souza Nery S, et al. Intra-arterial blood pressure response in hypertensive subjects during low-and high-intensity resistance exercise. Clinics. 2010;65(3):271–7. PubMed PMC

Liguori G, ACoS Medicine. ACSM’s guidelines for exercise testing and prescription. Lippincott Williams & Wilkins; 2020.

Moreira O, et al. Cardiovascular response to strength training is more affected by intensity than volume in healthy subjects. Revista Andaluza de Medicina del Deporte; 2017.

Haykowsky M, et al. Left ventricular wall stress during leg-press exercise performed with a brief Valsalva maneuver. Chest. 2001;119(1):150–4. PubMed

Palatini P, et al. Blood pressure changes during heavy-resistance exercise. J Hypertens. 1989;7:S72–73. PubMed

MacDougall J, et al. Arterial blood pressure response to heavy resistance exercise. J Appl Physiol. 1985;58(3):785–90. PubMed

Gotshall R et al. Noninvasive characterization of the blood pressure response to the double-leg press exercise. J Exerc Physiol Online. 2001;4(3).

Niewiadomski W, et al. Effects of a brief Valsalva manoeuvre on hemodynamic response to strength exercises. Clin Physiol Funct Imaging. 2012;32(2):145–57. PubMed

Sale D, et al. Comparison of blood pressure response to isokinetic and weight-lifting exercise. Eur J Appl Physiol Occup Physiol. 1993;67:115–20. PubMed

Pinto RR, Polito MD. Haemodynamic responses during resistance exercise with blood flow restriction in hypertensive subjects. Clin Physiol Funct Imaging. 2016;36(5):407–13. PubMed

Mohebbi H, Rohani H, Ghiasi A. Effect of involved muscle mass in resistance exercise on post exercise blood pressure and rate pressure product. Apunts Med De L’Esport. 2016;51(192):123–9.

Lamotte M, et al. Acute cardiovascular response to resistance training during cardiac rehabilitation: effect of repetition speed and rest periods. Eur J Prev Cardiol. 2010;17(3):329–36. PubMed

Gjovaag T et al. Resistance exercise and acute blood pressure responses. J Sports Med Phys Fit. 2015;20.

Gjøvaag TF, et al. Hemodynamic responses to resistance exercise in patients with coronary artery disease. Med Sci Sports Exerc. 2016;48(4):581–8. PubMed

Baum K, Rüther T, Essfeld D. Reduction of blood pressure response during strength training through intermittent muscle relaxations. Int J Sports Med. 2003;24(06):441–5. PubMed

Figueiredo T, et al. Influence of number of sets on blood pressure and heart rate variability after a strength training session. J Strength Conditioning Res. 2015;29(6):1556–63. PubMed

Polito MD, Farinatti PT. The effects of muscle mass and number of sets during resistance exercise on postexercise hypotension. J Strength Conditioning Res. 2009;23(8):2351–7. PubMed

Scher LM, et al. The effect of different volumes of acute resistance exercise on elderly individuals with treated hypertension. J Strength Conditioning Res. 2011;25(4):1016–23. PubMed

Novotna K, et al. Circuit training can have positive impact on muscle strength, balance, depression and fatigue in multiple sclerosis patients: A randomized controlled study. United J Phys Med Rehabilitation. 2019;1(1):1–8.

Margonato V, Cè E. Potential hypertensive risk during circuit training in normotensive and first-degree hypertensive subjects. Sport Sci Health. 2009;5:71–4.

Krzysztofik M, et al. Maximizing muscle hypertrophy: a systematic review of advanced resistance training techniques and methods. Int J Environ Res Public Health. 2019;16(24):4897. PubMed PMC

Kelleher AR, et al. The metabolic costs of reciprocal supersets vs. traditional resistance exercise in young recreationally active adults. J Strength Conditioning Res. 2010;24(4):1043–51. PubMed

Paz G. Strength performance parameters and muscle activat; 2016.

Fink J, et al. Physiological responses to agonist–antagonist superset resistance training. J Sci Sport Exerc. 2021;3:355–63.

Carregaro R, et al. Muscle fatigue and metabolic responses following three different antagonist pre-load resistance exercises. J Electromyogr Kinesiol. 2013;23(5):1090–6. PubMed

Schulz KF, Altman DG, Moher D. CONSORT 2010 statement: updated guidelines for reporting parallel group randomised trials. J Pharmacol Pharmacotherapeutics. 2010;1(2):100–7. PubMed PMC

Sorte AG, et al. Critical analysis of American heart association and European society of cardiology guidelines for hypertension. J Family Med Prim Care. 2023;12(8):1505–10. PubMed PMC

Unger T, et al. International society of hypertension global hypertension practice guidelines. Hypertension. 2020;75(6):1334–1357. PubMed

Williams MA, et al. Resistance exercise in individuals with and without cardiovascular disease: 2007 update: a scientific statement from the American heart association Council on clinical cardiology and Council on nutrition, physical activity, and metabolism. Circulation. 2007;116(5):572–84. PubMed

Sweileh WM. Bibliometric analysis of peer-reviewed literature on climate change and human health with an emphasis on infectious diseases. Globalization Health. 2020;16(1):44. PubMed PMC

Organization WH. The surveillance of risk factors report series (SuRF). SuRF Rep. 2005;2:22.

Whelton PK, et al. Harmonization of the American college of cardiology/american heart association and European society of Cardiology/European society of hypertension blood pressure/hypertension guidelines: comparisons, reflections, and recommendations. Eur Heart J. 2022;43(35):3302–11. PubMed PMC

Kobesova A, Valouchova P, Kolar P. Dynamic neuromuscular stabilization: exercises based on developmental kinesiology models. Funct Train Handb. 2014:25–51.

Ciolac EG, et al. Acute effects of continuous and interval aerobic exercise on 24-h ambulatory blood pressure in long-term treated hypertensive patients. Int J Cardiol. 2009;133(3):381–7. PubMed

Nascimento L, et al. Acute and chronic effects of aerobic exercise on blood pressure in resistant hypertension: study protocol for a randomized controlled trial. Trials. 2017;18:1–8. PubMed PMC

Anunciacao PG, et al. Blood pressure and autonomic responses following isolated and combined aerobic and resistance exercise in hypertensive older women. Clin Exp Hypertens. 2016;38(8):710–4. PubMed

Ghadieh AS, Saab B. Evidence for exercise training in the management of hypertension in adults. Can Fam Physician. 2015;61(3):233–9. PubMed PMC

Horvath IG, et al. Invasive validation of a new oscillometric device (Arteriograph) for measuring augmentation index, central blood pressure and aortic pulse wave velocity. J Hypertens. 2010;28(10):2068–75. PubMed

Baulmann J, et al. A new oscillometric method for assessment of arterial stiffness: comparison with tonometric and piezo-electronic methods. J Hypertens. 2008;26(3):523–8. PubMed

Sawka MN, Cheuvront SN, Carter R. Human water needs. Nutr Rev. 2005;63(suppl1):S30–9. PubMed

Mort JR, Kruse HR. Timing of blood pressure measurement related to caffeine consumption. Ann Pharmacother. 2008;42(1):105–10. PubMed

Higgins JP, Tuttle TD, Higgins CL. Energy beverages: content and safety. In: Mayo clinic proceedings; 2010. Elsevier. PubMed PMC

Virdis A, et al. Cigarette smoking and hypertension. Curr Pharm Design. 2010;16(23):2518–25. PubMed

Stand AP. Exercise and fluid replacement. Med Sci Sports Exerc. 2009;39(2):377–90. PubMed

Coelho-Júnior HJ et al. Acute effects of power and resistance exercises on hemodynamic measurements of older women. Clin Interv Aging. 2017:1103–14. PubMed PMC

Chukwuemeka UM, et al. Impact of squatting on selected cardiovascular parameters among college students. Sci Rep. 2024;14(1):5669. PubMed PMC

El-Gazzar HAE-M. The weightlifter’s blackout phenomenon. J Appl Sports Sci. 2023;13(1):1–3.

Blazek D, et al. Systematic review of intra-abdominal and intrathoracic pressures initiated by the Valsalva manoeuvre during high-intensity resistance exercises. Biology Sport. 2019;36(4):373–86. PubMed PMC

Du N, et al. Heart rate recovery after exercise and neural regulation of heart rate variability in 30–40 year old female marathon runners. J Sports Sci Med. 2005;4(1):9. PubMed PMC

Fletcher GF, et al. Exercise standards for testing and training: a scientific statement from the American heart association. Circulation. 2013;128(8):873–934. PubMed

Spronck B. Disentangling arterial stiffness and blood pressure. Heart Lung Circulation. 2021;30(11):1599–601. PubMed

Jurik R, Żebrowska A, Stastny P. Effect of an acute resistance training bout and long-term resistance training program on arterial stiffness: A systematic review and meta-analysis. J Clin Med. 2021;10(16):3492. PubMed PMC

Heffernan KS, et al. Arterial stiffness and baroreflex sensitivity following bouts of aerobic and resistance exercise. Int J Sports Med. 2007;28(03):197–203. PubMed

Tomschi F, et al. Acute effects of lower and upper body-resistance training on arterial stiffness, peripheral, and central blood pressure in young normotensive women. Sport Sci Health. 2018;14:357–63.

Nitzsche N, et al. Acute effects of different strength training protocols on arterial stiffness in healthy subjects. Group. 2016;6:197–202.

Thiebaud RS, et al. Effects of age on arterial stiffness and central blood pressure after an acute bout of resistance exercise. Eur J Appl Physiol. 2016;116:39–48. PubMed

Changes of abdominal wall tension across various resistance exercises during maximal and submaximal loads in healthy adults: a cross-sectional study

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ClinicalTrials.gov
NCT06047678