Enhancing stroke response in school children: Efficacy of the HOBIT program - a cluster randomized trial
Status PubMed-not-MEDLINE Language English Country United States Media electronic-ecollection
Document type Journal Article
PubMed
40248219
PubMed Central
PMC12005913
DOI
10.1016/j.pmedr.2025.103049
PII: S2211-3355(25)00088-9
Knihovny.cz E-resources
- Keywords
- Children, Cluster randomized trial, Health education, Intervention, School, Stroke awareness,
- Publication type
- Journal Article MeSH
Objective: Stroke treatment is often hampered by delayed Emergency Medical Services activation. Public campaigns to improve the response to stroke symptoms are either costly or not working. We evaluate the effectiveness of a school-based HOBIT program in improving Emergency Medical Services activation. Methods: This cluster randomized trial was conducted from May to June 2023 at 13 schools in the South Moravian region of Czechia. Schools were randomized to the HOBIT intervention or control group with a 3:1 ratio. Both groups had knowledge assessments at baseline and follow-up. The primary outcome was the percentage change from the pretest to the follow-up test in the intervention group compared to the control group in 4 domains: 1) knowledge, 2) self-efficacy, 3) outcome expectations, 4) behavioral intentions. Results: The baseline knowledge was greater than 50 % in most metrics except for knowledge of the FAST test, which was only 16 %. The intervention effect was 16 % (95 % CI 12-21) for knowledge, 10 % (95 % CI 4-15) for self-efficacy,10 % (95 % CI 5-15) for outcome expectations, 8 % (95 % CI 2-11) for behavioral intentions. Conclusions: In school children, even those with high baseline, "HOBIT" intervention can improve determinants and behavioral intentions of Emergency Medical Services activation for suspected stroke.
See more in PubMed
Bailey D.H., Duncan G.J., Cunha F., Foorman B.R., Yeager D.S. Persistence and fade-out of educational-intervention effects: mechanisms and potential solutions. Psychol Sci public Interes a J Am Psychol Soc. 2020;21(2):55–97. PubMed PMC
Bandura A. Guide for constructing self-efficacy scales (revised) Self-efficacy beliefs Adolesc. 2006;5:307–337.
Beal C.C., Flanders S.A., Bader S.G. Can children reduce delayed hospital arrival for ischemic stroke?: a systematic review of school-based stroke education. J. Neurosci. Nurs. 2016;48(3):E2–13. PubMed
Boden-Albala B., Quarles L.W. Education strategies for stroke prevention. Stroke. 2013;44(Suppl. 1):48–51. PubMed
Bray J.E., Straney L., Barger B., Finn J. Effect of public awareness campaigns on calls to ambulance across Australia. Stroke [Internet]. 2015;46(5):1377–1380. doi: 10.1161/STROKEAHA.114.008515. Available from: PubMed DOI
Di Carlo A, Baldereschi M, Bovis F, Piccardi B, Linoli G, Orlandi G, et al. Effect of an educational intervention to increase stroke awareness among Italian high school students: A prospective study in Tuscany. Eur Stroke J [Internet]. 2023;23969873231175404. Available from: doi:10.1177/23969873231175405. PubMed DOI PMC
Eisinga R., Te Grotenhuis M., Pelzer B. The reliability of a two-item scale: Pearson, Cronbach, or spearman-Brown? Int J Public Health [Internet]. 2013;58(4):637–642. doi: 10.1007/s00038-012-0416-3. Available from: PubMed DOI
Faiz K.W., Sundseth A., Thommessen B., Rønning O.M. Prehospital delay in acute stroke and TIA. Emerg. Med. J. 2013;30(8):669–674. PubMed
Faul F., Erdfelder E., Buchner A., Lang A.-G. Statistical power analyses using G*power 3.1: tests for correlation and regression analyses. Behav. Res. Methods. 2009;41:1149–1160. PubMed
Feigin V.L., Brainin M., Norrving B., Martins S., Sacco R.L., Hacke W., et al. World stroke organization (WSO): global stroke fact sheet 2022. Int. J. Stroke. 2022;17(1):18–29. PubMed
Higgin J., LT Eldridge S. Including variants on randomized trials. In: Cochrane Handbook for Systematic Reviews of Interventions Version 64 [Internet]. Cochrane. 2023. www.training.cochrane.org/handbook Available from:
Jakasania A., Lahariya C., Pandya C., Raut A.V., Sharma R., K S, et al. School health Services in India: status, challenges and the way forward. Indian J Pediatr [Internet]. 2023;90(S1):116–124. Available from: https://link.springer.com/10.1007/s12098-023-04852-x. PubMed
Kandakai T.L., King K.A. Perceived self-efficacy in performing lifesaving skills: an assessment of the american red cross’s responding to emergencies course. J Heal Educ. 1999;30(4):235–241.
Kleindorfer D.O., Miller R., Moomaw C.J., Alwell K., Broderick J.P., Khoury J., et al. Designing a message for public education regarding stroke. Stroke [Internet]. 2007;38(10):2864–2868. doi: 10.1161/STROKEAHA.107.484329. Available from: PubMed DOI
Kleszczewska D., Porwit K., Boberova Z., Sigmund E., Vasickova J., Paakkari L. Adolescent health literacy and Neighbourhood features: HBSC findings from Czech Republic, Poland, and Slovakia. Int. J. Environ. Res. Public Health. 2021;18 PubMed PMC
Komolafe M.A., Olorunmoteni O.E., Fehintola F.O. Effect of health education on level of awareness and knowledge of Nigerian in-school adolescents on stroke and its risk factors. J Stroke Cerebrovasc Dis [Internet]. 2020;29(5) Available from: https://www.sciencedirect.com/science/article/pii/S1052305720301348. PubMed
Lahariya C. Preventive medicine: initium Salutis renaissance. Prev Med Res Rev [Internet]. 2024;1(1). Available from: https://journals.lww.com/pmrr/fulltext/2024/01010/preventive_medicine__initium_salutis_renaissance.1.aspx.
Li X, Liu Y, Vrudhula A, Liu R, Zhao J. Middle school students effectively improve stroke knowledge and pass them to family members in China using stroke 1-2-0. Front Neurol [Internet]. 2020 Apr 8;11. Available from: https://www.frontiersin.org/article/10.3389/fneur.2020.00203/full. PubMed PMC
Marto J.P., Borbinha C., Filipe R., Calado S., Viana-Baptista M. Impact of stroke education on middle school students and their parents: a cluster randomized trial. Int J stroke Off J Int Stroke Soc. 2017;12(4):401–411. PubMed
Masztalewicz M., Nowacki P., Kotlęga D., Bajer-Czajkowska A. Early emergency medical service calls for stroke: was the long-term education program based on the experience of West Pomerania successful? J stroke Cerebrovasc Dis Off J Natl Stroke Assoc. 2016;25(2):254–258. PubMed
McCambridge J., Witton J., Elbourne D.R. Systematic review of the Hawthorne effect: new concepts are needed to study research participation effects. J Clin Epidemiol [Internet]. 2014;67(3):267–277. Available from: https://www.sciencedirect.com/science/article/pii/S0895435613003545. PubMed PMC
Mellon L., Hickey A., Doyle F., Dolan E., Williams D. Can a media campaign change health service use in a population with stroke symptoms? Examination of the first Irish stroke awareness campaign. Emerg. Med. J. 2014;31(7):536–540. PubMed
Mikulík R., Bar M., Bělašková S., Černík D., Fiksa J., Herzig R., et al. Ultrashort door-to-needle time for intravenous thrombolysis is safer and improves outcome in the Czech Republic: Nationwide study 2004 to 2019. J Am Heart Assoc [Internet]. 2022;11(10) Available from: https://www.ahajournals.org/doi/10.1161/JAHA.121.023524. PubMed PMC
Miller E.T., King K.A., Miller R., Kleindorfer D. FAST stroke prevention educational program for middle school students: pilot study results. J. Neurosci. Nurs. 2007;39(4):236–243. PubMed
Morgenstern L.B., Gonzales N.R., Maddox K.E., Brown D.L., Karim A.P., Espinosa N., et al. A randomized, controlled trial to teach middle school children to recognize stroke and call 911. Stroke [Internet]. 2007;38(11):2972–2978. Available from: https://www.ahajournals.org/doi/10.1161/STROKEAHA.107.490078. PubMed
Nishijima H, Ueno T, Kon T, Haga R, Funamizu Y, Arai A, et al. Effects of educational television commercial on pre-hospital delay in patients with ischemic stroke wore off after the end of the campaign. J Neurol Sci [Internet]. 2017;381:117–8. Available from: https://www.sciencedirect.com/science/article/pii/S0022510X17337334. PubMed
Norrving B., Barrick J., Davalos A., Dichgans M., Cordonnier C., Guekht A., et al. Action plan for stroke in Europe 2018–2030. Eur Stroke J [Internet]. 2018;3(4):309–336. Available from: http://journals.sagepub.com/doi/10.1177/2396987318808719. PubMed PMC
Ohyama S, Yokota C, Miyashita F, Amano T, Inoue Y, Shigehatake Y, et al. Effective education materials to advance stroke awareness without teacher participation in junior high school students. J Stroke Cerebrovasc Dis [Internet]. 2015;24(11):2533–8. Available from: https://linkinghub.elsevier.com/retrieve/pii/S1052305715003870. PubMed
Ottawa C., Sposato L.A., Nabbouh F., Saposnik G. Stroke preparedness in children: translating knowledge into behavioral intent: a systematic review and meta-analysis. Int. J. Stroke. 2015;10(7):1008–1013. PubMed
Sakamoto Y., Yokota C., Miyashita F., Amano T., Shigehatake Y., Oyama S., et al. Effects of stroke education using an animated cartoon and a manga on elementary school children. J Stroke Cerebrovasc Dis [Internet]. 2014;23(7):1877–1881. doi: 10.1016/j.jstrokecerebrovasdis.2014.02.015. Available from: PubMed DOI
Seo A.R., Song H., Lee W.J., Park K.N., Moon J., Kim D. Factors associated with delay of emergency medical services activation in patients with acute stroke. J Stroke Cerebrovasc Dis [Internet]. 2021;30(1) doi: 10.1016/j.jstrokecerebrovasdis.2020.105426. Available from: PubMed DOI
Sheeran P., Maki A., Montanaro E., Avishai-Yitshak A., Bryan A., Klein W.M.P., et al. The impact of changing attitudes, norms, and self-efficacy on health-related intentions and behavior: a meta-analysis. Heal Psychol [Internet]. 2016;35(11):1178–1188. Available from: http://doi.apa.org/getdoi.cfm?doi=10.1037/hea0000387. PubMed
Skolarus L.E., Murphy J.B., Dome M., Zimmerman M.A., Bailey S., Fowlkes S., et al. Creating a novel video vignette stroke preparedness outcome measure using a community-based participatory approach. Health Promot Pract [Internet]. 2015;16(4):533–539. Available from: http://journals.sagepub.com/doi/10.1177/1524839914557032. PubMed PMC
Tan J., Ramazanu S., Liaw S.Y., Chua W.L. Effectiveness of public education campaigns for stroke symptom recognition and response in non-elderly adults: a systematic review and Meta-analysis. J Stroke Cerebrovasc Dis [Internet]. 2022;31(2) https://linkinghub.elsevier.com/retrieve/pii/S1052305721006121 Available from: PubMed
Tekyol D, Altundağ İ, Efe Y, Kılıç M, Öncü T, Pul MF, et al. Investigation of an alternative education module in raising middle school student's awareness of acute stroke. Clin Neurol Neurosurg [Internet]. 2023 Feb;225:107565. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0303846722004462. PubMed
Teuschl Y., Brainin M. Stroke education: discrepancies among factors influencing prehospital delay and stroke knowledge. Int. J. Stroke. 2010;5(3):187–208. PubMed
Tomari S., Yokota C., Nishimura K., Hino T., Ohyama S., Arimizu T., et al. Effects of school-based intervention by emergency medical technicians on students and their parents: a community-based prospective study of the Akashi project. BMJ Open. 2017;7(10):1–6. PubMed PMC
Volevach E., Schneider F., Maršálková H., Mikulik R. The use of intervention mapping to guide the development of a school-based intervention to improve emergency medical services activation for stroke. BMC Public Health [Internet]. 2024;24(1):3322. Available from: https://www.tandfonline.com/doi/full/10.1080/13645579.2023.2175921. PubMed PMC
Vondráčková L., Mikulík R. Public stroke education: current status worldwide and projects to increase awareness in the Czech Republic. Cor Vasa [Internet]. 2017;59(6):e546–e552. (Available from: http://10.0.3.248/j.crvasa.2016.12.004)
Williams O., Leighton-Herrmann Quinn E., Teresi J., Eimicke J.P., Kong J., Ogedegbe G., et al. Improving community stroke preparedness in the HHS (hip-hop stroke) randomized clinical trial. Stroke [Internet]. 2018;49(4):972–979. Available from: https://www.ahajournals.org/doi/10.1161/STROKEAHA.117.019861. PubMed PMC