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Catheters and Tools with Pulsed Field Ablation-Pulmonary Vein Isolation and Nanosecond Pulse Field Ablation

. 2025 Jun ; 17 (2) : 273-285. [epub] 20250317

Language English Country United States Media print-electronic

Document type Journal Article, Review

Links

PubMed 40412876
DOI 10.1016/j.ccep.2025.02.015
PII: S1877-9182(25)00017-6
Knihovny.cz E-resources

Pulse field ablation (PFA) has gained attention in the field of atrial fibrillation catheter treatment recently. All currently used or developed technologies use ultrashort pulses (on the order of microseconds). The Emerging CellFX System (Pulse Biosciences, Inc, Inc) utilizes nanosecond PFA (nsPFA) and is thus several orders of magnitude shorter than the initial PFA systems. There are several potential advantages of nsPFA over microsecond PFA such as deeper penetration of the electric field into tissue, creating larger and deeper ablation zones while depositing less overall energy and heat, faster treatment, and less muscle stimulation or nerve capture.

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