Cardiovascular disease (CVD) is a leading cause of death worldwide. A key area of interest in CVD prevention is novel digital health technologies, primarily mobile health (mHealth) applications and wearable devices, that are rapidly transforming the methods of preventing and managing CVD. Studies have shown the success of smartphone applications, such as the RITMIA app (Heart Sentinel™, Parma, Italy), in successfully detecting atrial fibrillation (Afib) compared to a classic 12-lead electrocardiogram (ECG). mHealth devices should integrate these factors, based on artificial intelligence (AI) and driven by chatbots, to encourage patients to use technology through interactive, real-world, motivational, and timely feedback. Data from mHealth clinical research indicate improved medication adherence, weight control, and self-care among patients. This review highlights mHealth and wearable devices in CVD prevention, providing foresight into cardiovascular health conditions through continuous monitoring, early detection, and improved patient engagement. Additionally, it examines challenges, including ethical, regulatory, and accessibility issues, that need to be addressed before their widespread adoption. In the future, the priority must be integration with healthcare systems and equitable access. A thorough search was conducted using reputable databases such as Scopus, PubMed, and Google Scholar. Articles from 2015 to 2025, along with an article from 2002 published in reputable peer-reviewed journals, were analyzed and contextually used. We also refined our search terms and used high-quality English articles to achieve this.

Acute Medicine Cumberland Infirmary Carlisle GBR

Anaesthesia Chris Hani Baragwanath Academic Hospital Johannesburg ZAF

Cardiology National Heart Institute Giza EGY

Cardiovascular Service Line Morristown Medical Center Morristown USA

Dermatology Bahria University Medical and Dental College Karachi PAK

Family Medicine Washington University of Health and Science San Pedro BLZ

General Medicine Shirdi Sai Hospital Bengaluru IND

Internal Medicine Alluri Sitarama Raju Academy of Medical Sciences Eluru IND

Internal Medicine Barts and the London School of Medicine and Dentistry Queen Mary University of London London GBR

Internal Medicine Charles University Hradec Kralove CZE

Internal Medicine Dorset County Hospital Dorchester GBR

Medicine and Surgery University of Medical Sciences and Technology Khartoum SDN

School of Medicine University College Dublin Dublin IRL

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