Everolimus [everolimus]
topical
190
- Terms
-
Afinitor
Certican
RAD001
Zortress
-
40-O-(2-hydroxyethyl)-rapamycin
Afinitor
Certican
RAD 001
RAD001
SDZ RAD
SDZ-RAD
Zortress
Persistent link
https://www.medvik.cz/link/D000068338
Definition
A derivative of sirolimus and an inhibitor of TOR SERINE-THREONINE KINASES. It is used to prevent GRAFT REJECTION in heart and kidney transplant patients by blocking cell proliferation signals. It is also an ANTINEOPLASTIC AGENT.
- DUI
- D000068338 MeSH Browser
- CUI
- M000602394
- History note
- 2016 (1997)
- Public note
- 2016; EVEROLIMUS was indexed under SIROLIMUS 1998-2015; and under POLYENES 1997-1998
Allowable subheadings
- AD
- administration & dosage 47
- AE
- adverse effects 42
- AG
- agonists 0
- AA
- analogs & derivatives 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 1
- BL
- blood 2
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- EC
- economics 0
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 1
- PK
- pharmacokinetics 13
- PD
- pharmacology 26
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 89
- TO
- toxicity 2
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs