Sofosbuvir [sofosbuvir]

topical
48
Terms

Harvoni
Sovaldi

 

2-((5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy)phenoxyphosphorylamino)propionic acid isopropyl ester
GS-7977
PSI 7977
PSI-7977
PSI7977
Sovaldi

Definition

A uridine monophosphate analog inhibitor of HEPATITIS C VIRUS (HCV) polymerase NS5B that is used as an ANTIVIRAL AGENT in the treatment of CHRONIC HEPATITIS C.

DUI
D000069474 MeSH Browser
CUI
M0551450
History note
2016 (2010)
Public note
2016; SOFOSBUVIR was indexed under URIDINE MONOPHOSPHATE 2010-2015

D Chemicals and Drugs
D03.383.742 Pyrimidines 959
D03.383.742.686 Pyrimidine Nucleotides 14
D03.383.742.686.850 Uracil Nucleotides 12
D03.383.742.686.850.877 Uridine Monophosphate 21
D03.383.742.686.850.877.500 Sofosbuvir 48
D13.695 Nucleotides 357
D13.695.740.850 Uracil Nucleotides 12
D13.695.740.850.877 Uridine Monophosphate 21
D13.695.740.850.877.500 Sofosbuvir 48
D13.695.827 Ribonucleotides 18
D13.695.827.919 Uracil Nucleotides 12
D13.695.827.919.877 Uridine Monophosphate 21
D13.695.827.919.877.500 Sofosbuvir 48