ETS Motif [ETS motiv]

topical
Terms

ETS doména

 

ETS Domain
Helix-Turn-Helix, ETS-Type Domain Containing

Persistent link   https://www.medvik.cz/link/D000071419
Definition

A helix-turn-helix motif characterized by three alpha-helices and four-stranded beta-sheets arranged in the order alpha1-beta1-beta2-alpha2-alpha3-beta3-beta4. The third alpha-helix contacts the major groove of DNA. The ETS motif and the flanking amino acid sequences of Ets proteins influence the binding affinity, and the alteration of a single amino acid in the Ets domain can change its DNA binding specificity.

DUI
D000071419 MeSH Browser
CUI
M000614527
Previous indexing
Amino Acid Sequence (1990-2016); Proto-Oncogene Proteins (1990-2016); Transcription Factors (1990-2016)
History note
2017
Public note
2017

Allowable subheadings

DE
drug effects
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects

G Phenomena and Processes
G01 Physical Phenomena 79
G02 Chemical Phenomena 308
G02.111 Biochemical Phenomena 370
G02.111.570 Molecular Structure 1 332
G02.111.570.820 Molecular Conformation 228
G02.111.570.820.709 Protein Conformation 558
G02.111.570.820.709.275 Protein Structural Elements 1
G02.111.570.820.709.275.500 Amino Acid Motifs 101
G02.111.570.820.709.275.500.360 Helix-Loop-Helix Motifs
G02.111.570.820.709.275.500.360.360 Helix-Turn-Helix Motifs 1
G02.111.570.820.709.275.500.360.360.500 ETS Motif
G03 Metabolism 1 199
G03 Metabolic Phenomena obsolete
G04 Cell Physiological Phenomena 515
G05 Genetic Phenomena 135
G06 Microbiological Phenomena 96
G07 Physiological Phenomena 176
G08 Reproductive and Urinary Physiological Phenomena 18
G09 Circulatory and Respiratory Physiological Phenomena 94
G10 Digestive System and Oral Physiological Phenomena 4
G11 Musculoskeletal and Neural Physiological Phenomena 17
G12 Immune System Phenomena 249
G13 Integumentary System Physiological Phenomena 14
G14 Ocular Physiological Phenomena 148
G15 Plant Physiological Phenomena 158
G16 Biological Phenomena 130
G17 Mathematical Concepts 66

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