APOBEC-3G Deaminase [deaminasa APOBEC-3G]
- Terms
-
deamináza APOBEC-3G
deamináza APOBEC3G
protein CEM15
-
APOBEC-3G dC-dU Editing Enzyme
APOBEC-3G Protein
APOBEC-Related Cytidine Deaminase
APOBEC-Related Protein
APOBEC3G Deaminase
APOBEC3G Protein
CEM15 Protein
An APOBEC deaminase that functions as an inhibitor of RETROVIRIDAE replication and inhibits the mobility of RETROTRANSPOSONS via deaminase-dependent and independent mechanisms. It is selective for SINGLE-STRANDED DNA and does not deaminate double-stranded DNA or single or DOUBLE-STRANDED RNA. It exhibits potent antiviral activity against VIF PROTEIN deficient HIV-1 through the creation of hypermutations in the VIRAL DNA. It also has anti-viral activity against SIMIAN IMMUNODEFICIENCY VIRUSES and HEPATITIS B VIRUS.
- DUI
- D000071480 MeSH Browser
- CUI
- M000614859
- Previous indexing
- Cytidine Deaminase (2007-2016)
- History note
- 2017
- Public note
- 2017
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
APOBEC3G protein, human Chemical MeSH Browser
APOBEC3G protein, mouse Chemical MeSH Browser