Non-visual system arrestins that negatively regulate G-PROTEIN-COUPLED RECEPTORS (GPCRs) and may also function independently of GPCR signaling. They bind and recruit many different signaling factors, including MITOGEN-ACTIVATED PROTEIN KINASES; SRC-FAMILY-KINASES; and FILAMIN to GPCRs and may recognize different phosphorylation states of the receptors to determine the specificity of the cellular response to signaling.

DUI

D000071557 MeSH Prohlížeč

CUI

M000615063

Historická pozn.

2017 (1992)

Veřejná pozn.

2017; BETA-ARRESTINS was indexed under ARRESTINS 1996-2016 and under ANTIGENS and EYE PROTEINS 1992-1996