AC133 Antigen [antigen AC133]
- Terms
-
antigen AC133-2
antigen AC141
antigen CD133
CD133
prominin 1
-
AC133-1 Antigen
AC133-2 Antigen
AC141 Antigen
CD133 Antigen
Fudenine
Prominin
Prominin-1
Prominin-Like PROML1
PROML1
A member of the prominin family, AC133 Antigen is a 5-transmembrane antigen occurring as several isoforms produced by alternative splicing which are processed into mature forms. In humans, it is expressed as a subset of CD34 (bright) human hematopoietic stem cells and CD34 positive leukemias. Functionally, it is associated with roles in cell differentiation, proliferation, and apoptosis. Specifically, it regulates the organization of apical plasma membrane in epithelial cells, disk morphogenesis during early retinal development, MAPK and Akt signaling pathways, and in cholesterol metabolism.
- DUI
- D000071916 MeSH Browser
- CUI
- M0288458
- History note
- 2017(1998)
- Public note
- 2017; AC133 ANTIGEN was indexed under GLYCOPROTEINS, PEPTIDES and ANTIGENS, CD 1998-2016
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis 1
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 1
- HI
- history
- IM
- immunology 1
- IP
- isolation & purification
- ME
- metabolism 6
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
PROM1 protein, human Chemical MeSH Browser
Prom1 protein, mouse Chemical MeSH Browser
Prom1 protein, rat Chemical MeSH Browser