thrombospondiny [Thrombospondins]
tematický
7
- Termíny
-
Thrombospondin
Perzistentní odkaz
https://www.medvik.cz/link/D019699
Definice
A family of related, adhesive glycoproteins which are synthesized, secreted, and incorporated into the extracellular matrix of a variety of cells, including alpha granules of platelets following thrombin activation and endothelial cells. They interact with a number of BLOOD COAGULATION FACTORS and anticoagulant factors. Five distinct forms have been identified, thrombospondin 1, -2, -3, -4, and cartilage oligomeric matrix protein (COMP). They are involved in cell adhesion, platelet aggregation, cell proliferation, angiogenesis, tumor metastasis, VASCULAR SMOOTH MUSCLE growth, and tissue repair.
- Anotace
- membrane glycoproteins; THROMBOSPONDIN 1 is also available
- DUI
- D019699 MeSH Prohlížeč
- CUI
- M0029253
- Předchozí užití
- Glycoproteins (1981-1989); Membrane Glycoproteins (1989-1997); Platelet Membrane Glycoproteins (1992-1993)
- Historická pozn.
- 98; see THROMBOSPONDINS (NM) 1981-97
- Veřejná pozn.
- 98; THROMBOSPONDIN was indexed under MEMBRANE GLYCOPROTEINS 1989-97, PLATELET MEMBRANE GLYCOPROTEINS 1992-93, & GLYCOPROTEINS 1981-89
Povolená podhesla
- AG
- agonisté 0
- AN
- analýza 0
- AI
- antagonisté a inhibitory 0
- AD
- aplikace a dávkování 0
- BI
- biosyntéza 2
- CS
- chemická syntéza 0
- CH
- chemie 0
- HI
- dějiny 0
- EC
- ekonomika 0
- PK
- farmakokinetika 0
- PD
- farmakologie 0
- PH
- fyziologie 0
- GE
- genetika 1
- IM
- imunologie 0
- IP
- izolace a purifikace 0
- CL
- klasifikace 0
- BL
- krev 0
- ME
- metabolismus 3
- UR
- moč 0
- CF
- mozkomíšní mok 0
- DF
- nedostatek 0
- ST
- normy 0
- PO
- otrava 0
- AE
- škodlivé účinky 0
- TU
- terapeutické užití 0
- TO
- toxicita 0
- DE
- účinky léků 0
- RE
- účinky záření 0
- UL
- ultrastruktura 0
- SD
- zásobování a distribuce 0
...
Výskyt v záznamech Medvik
D
Chemikálie a léčiva
D09.400.430.890.015
antigen CD83
D09.400.430.890.017
podoplanin
D09.400.430.890.331
fertiliny
D09.400.430.890.469
buněčný receptor 1 viru hepatitidy A
D09.400.430.890.895.400
R-spondiny
D09.400.430.890.942
uroplakiny
D09.400.430.890.995
glykoproteiny zona pellucida
D12.776.395.550.015
antigen CD83
D12.776.395.550.017
podoplanin
D12.776.395.550.331
fertiliny
D12.776.395.550.469
buněčný receptor 1 viru hepatitidy A
D12.776.395.550.895.400
R-spondiny
D12.776.395.550.942
uroplakiny
D12.776.395.550.995
glykoproteiny zona pellucida
D12.776.543.550.068
antigen CD83
D12.776.543.550.079
podoplanin
D12.776.543.550.170
antigeny CD70
D12.776.543.550.435
buněčný receptor 1 viru hepatitidy A
D12.776.543.550.779
SLC4A proteiny
D12.776.543.550.895.400
R-spondiny
D12.776.543.550.942
uroplakiny
D12.776.543.550.995
glykoproteiny zona pellucida