Transcription Factor HES-1 [transkripční faktor HES1]

topical
2
Terms

transkripční faktor HES-1

 

Hairy and Enhancer of Split 1 Protein
Hairy-Like Transcription Factor

Definition

A basic-helix-loop-helix transcription factor that functions as a transcriptional repressor for genes transcribed by bHLH proteins. For example, it may negatively regulate MYOGENESIS by inhibiting MyoD1 and ASH1 proteins. It is also required for the stability of FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS and their localization to the cell nucleus in response to DNA DAMAGE.

DUI
D000072056 MeSH Browser
CUI
M000616269
Previous indexing
Basic Helix-Loop-Helix Transcription Factors (1994-2016); Homeodomain Proteins (1994-2016)
History note
2017
Public note
2017

D Chemicals and Drugs
D12.776 Proteins 2 575
D12.776.260 DNA-Binding Proteins 556
D12.776.260.103.249 ARNTL Transcription Factors 14
D12.776.260.103.562 CLOCK Proteins 19
D12.776.260.103.625 Hypoxia-Inducible Factor 1 19
D12.776.260.103.750 Myogenic Regulatory Factors 6
D12.776.260.103.782 Nuclear Receptor Coactivator 1 4
D12.776.260.103.813 Proto-Oncogene Proteins c-myc 66
D12.776.260.103.844 Transcription Factor HES-1 2
D12.776.260.103.906 Twist Transcription Factors
D12.776.260.103.937 Upstream Stimulatory Factors
D12.776.930 Transcription Factors 727
D12.776.930.125.249 ARNTL Transcription Factors 14
D12.776.930.125.562 CLOCK Proteins 19
D12.776.930.125.625 Hypoxia-Inducible Factor 1 19
D12.776.930.125.750 Myogenic Regulatory Factors 6
D12.776.930.125.813 Proto-Oncogene Proteins c-myc 66
D12.776.930.125.844 Transcription Factor HES-1 2
D12.776.930.125.906 Twist Transcription Factors
D12.776.930.125.937 Upstream Stimulatory Factors