Smoothened Receptor [receptor Smoothened]

topical
4
Terms

Smoothened Protein
Smoothened Receptors

Definition

A frizzled-like, G-protein-coupled receptor that associates with PATCHED RECEPTORS to transduce signals from HEDGEHOG PROTEINS and initiate hedgehog signaling to ZINC FINGER PROTEIN GLI1. It may normally inhibit signaling in the absence of SONIC HEDGEHOG PROTEIN binding to PATCHED RECEPTOR-1.

DUI
D000072086 MeSH Browser
CUI
M000616322
Previous indexing
Receptors, G-Protein-Coupled (2004-2016)
History note
2017
Public note
2017

D Chemicals and Drugs
D12.776 Proteins 2 575
D12.776.543 Membrane Proteins 846
D12.776.543.750 Receptors, Cell Surface 511
D12.776.543.750.695 Receptors, G-Protein-Coupled 98
D12.776.543.750.695.017 Frizzled Receptors 12
D12.776.543.750.695.017.500 Smoothened Receptor 4
D12.776.543.750.850 Receptors, Wnt
D12.776.543.750.850.500 Frizzled Receptors 12
D12.776.543.750.850.500.500 Smoothened Receptor 4