Proteiny na povrchu buněk, které s vysokou afinitou vážou signální molekuly vně buňky a převádějí tuto extracelulární událost na jeden nebo více intracelulárních signálů, jež mění chování cílové buňky (z Alberts, Molecular Biology of the Cell, 2. vydání, s. 693-5). Receptory na povrchu buněk na rozdíl od enzymů chemicky nemění své ligandy.

Cell surface proteins that bind signalling molecules external to the cell with high affinity and convert this extracellular event into one or more intracellular signals that alter the behavior of the target cell (From Alberts, Molecular Biology of the Cell, 2nd ed, pp693-5). Cell surface receptors, unlike enzymes, do not chemically alter their ligands.

Anotace

general or unspecified; prefer specifics; coord IM with specific endogenous substance (IM); for hormone receptors in general coord HORMONES (IM) and RECEPTORS, CELL SURFACE (IM) or RECEPTORS, CYTOPLASMIC AND NUCLEAR (IM), for receptors of specific hormones, coord specific hormone or hormone group (IM) and precoord hormone receptor (e.g., RECEPTORS, ALDOSTERONE) (IM) or precoord hormone-group receptor (e.g., RECEPTORS, GLUCOCORTICOID) (IM)

DUI

D011956 MeSH Prohlížeč

CUI

M0018574

Předchozí užití

Receptors, Drug (1968-1972)

Historická pozn.

94; was RECEPTORS, ENDOGENOUS SUBSTANCES 1983-93; was RECEPTORS, HORMONE 1973-82; CELL RECEPTORS & RECEPTORS, BIOLOGIC were see RECEPTORS, ENDOGENOUS SUBSTANCES 1985-93; HORMONE RECEPTORS was see RECEPTORS, ENDOGENOUS SUBSTANCES 1975-93

Online pozn.

use RECEPTORS, CELL SURFACE to search RECEPTORS, ENDOGENOUS SUBSTANCES 1983-93, CELL RECEPTORS 1985-93, HORMONE RECEPTORS 1975-93, RECEPTORS BIOLOGICAL 1985-93, & RECEPTORS, HORMONE 1973-93

Veřejná pozn.

94; was RECEPTORS, ENDOGENOUS SUBSTANCES 1983-93; was RECEPTORS, HORMONE 1973-82; CELL RECEPTORS & RECEPTORS, BIOLOGIC were see RECEPTORS, ENDOGENOUS SUBSTANCES 1985-93; HORMONE RECEPTORS was see RECEPTORS, ENDOGENOUS SUBSTANCES 1975-93