ADAM17 Protein [protein ADAM17]
- Terms
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antigen CD156b
enzym konvertující faktor TNF-alfa
enzym uvolňující prozánětlivý cytokin TNF-alfa
metaloproteáza ADAM17/TACE
protein ADAM 17
TACE
TNF-alfa konvertující enzym
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ADAM-17
ADAM-17 Protein
CD156b Antigen
Disintegrin and Metalloproteinase Domain-Containing Protein 17
TACA (Enzyme)
TACE (Enzyme)
TNF-alpha Convertase
TNF-alpha Converting Enzyme
Tumor Necrosis Factor Alpha Convertase
Tumor Necrosis Factor-alpha Convertase
Tumor Necrosis Factor-alpha Converting Enzyme
A disintegrin and metalloproteinase domain-containing protein that cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA to its mature form. It cleaves several other CELL SURFACE PROTEINS, including INTERLEUKIN-1 RECEPTOR TYPE II; TRANSFORMING GROWTH FACTOR ALPHA; L-SELECTIN; MUCIN-1; and AMYLOID BETA-PROTEIN PRECURSOR. It can also function as an activator of the Notch signaling pathway by mediating the cleavage of NOTCH RECEPTORS.
- DUI
- D000072198 MeSH Browser
- CUI
- M0265247
- History note
- 2017 (1996)
- Public note
- 2017; ADAM17 PROTEIN was indexed under ADAM PROTEINS 2005-2016, and under METALLOENDOPEPTIDASES 1996-2005
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 6
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 9
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology 1
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
ADAM17 protein, human Chemical MeSH Browser
Adam17 protein, mouse Chemical MeSH Browser
Adam17 protein, rat Chemical MeSH Browser