Placenta Growth Factor [placentární růstový faktor]

topical
19
Terms

Placenta Growth Factor
PlGF

 

Placenta Growth Factor, PLGF-1 Isoform
Placenta Growth Factor, PLGF-2 Isoform
Placenta Growth Factor, PLGF-3 Isoform
Placenta Growth Factor, PLGF-4 Isoform

Definition

An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer.

DUI
D000072483 MeSH Browser
CUI
M0193636
History note
2017 (1991)
Public note
2017; PLACENTA GROWTH FACTOR was indexed under PREGNANCY PROTEINS 1991-2016

PGF protein, human Chemical MeSH Browser

Pgf protein, mouse Chemical MeSH Browser

Pgf protein, rat Chemical MeSH Browser