Solute Carrier Family 22 Member 5 [rodina nosičů rozpuštěných látek 22, člen 5]
- Terms
-
protein OCTN2
protein SLC22A5
-
High-Affinity Carnitine Transporter
OCTN2 Protein
Organic Cation-Carnitine Transporter 2
SLC22A5 Protein
Sodium-Dependent Carnitine Cotransporter
A high-affinity, ATP-binding, co-transporter for CARNITINE that is highly expressed in kidney, skeletal muscle, heart, and placental tissues. It transports one sodium ion with one carnitine molecule. It has a lower affinity for other organic cations and transports them independently of sodium. Mutations in the SLC22A5 gene are associated with systemic carnitine deficiency.
- DUI
- D000074058 MeSH Browser
- CUI
- M000625386
- Previous indexing
- Carrier Proteins (1998-2017); Organic Cation Transport Proteins (2004-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 1
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 2
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
SLC22A5 protein, human Chemical MeSH Browser
Slc22a5 protein, mouse Chemical MeSH Browser
Slc22a5 protein, rat Chemical MeSH Browser