Solute Carrier Organic Anion Transporter Family Member 1B3 [protein OATP1B3]
- Terms
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jaterní přenašeč organických aniontů 2
jaterní transportér organických aniontů 2
protein OATP8
protein SLC21A8
protein SLCO1B3
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Liver-Specific Organic Anion Transporter-2
OATP1B3 Protein
OATP8 Protein
SLC21A8 Protein
SLCO1B3 Protein
Solute Carrier Family 21 Member 8 Protein
A sodium-independent organic anion transporter that functions in the uptake of various drugs and endogenous compounds including ESTRADIOL; TAUROCHOLATE; LEUKOTRIENE C4; and METHOTREXATE. It also functions in clearing BILE ACIDS and organic anions from the liver. Mutations in the SLCO1B3 gene are associated with Rotor Type HYPERBILIRUBINEMIA.
- DUI
- D000074542 MeSH Browser
- CUI
- M000626958
- Previous indexing
- Organic Anion Transporters, Sodium-Independent (2002-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 1
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
SLCO1B3 protein, human Chemical MeSH Browser
Slco1b2 protein, rat Chemical MeSH Browser