Bestrophins [bestrofiny]
- Terms
-
BEST1
protein bestrofin-1
protein bestrofin-2
-
BEST-1 Protein
BEST-2 Protein
Bestrophin
Bestrophin Family
Bestrophin Proteins
Bestrophin-1
Bestrophin-2
A protein family characterized by a highly conserved N-terminus and four to six transmembrane helices; they function as bicarbonate permeable, calcium-activated chloride channels. Bestrophin-1 (BEST-1) and bestrophin-2 are highly expressed in human RETINAL PIGMENT EPITHELIUM cells and mutations in the BEST-1 gene are associated with VITELLIFORM MACULAR DYSTROPHY, TYPE 2.
- DUI
- D000075002 MeSH Browser
- CUI
- M000628883
- Previous indexing
- Chloride Channels (1999-2017); Eye Proteins (1999-2017)
- History note
- 2018
- Public note
- 2018
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 1
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
BEST1 protein, human Chemical MeSH Browser
BEST2 protein, human Chemical MeSH Browser
BEST3 protein, human Chemical MeSH Browser
BEST4 protein, human Chemical MeSH Browser
Best1 protein, mouse Chemical MeSH Browser
Best1 protein, rat Chemical MeSH Browser
Best2 protein, mouse Chemical MeSH Browser
Best2 protein, rat Chemical MeSH Browser
Best3 protein, rat Chemical MeSH Browser
best1 protein, Drosophila Chemical MeSH Browser
best2 protein, Drosophila Chemical MeSH Browser
best3 protein, Drosophila Chemical MeSH Browser