Decitabine [decitabin]
topical
11
- Terms
-
Dacogen
-
2'-Deoxy-5-azacytidine
5-Aza-2'-deoxycytidine
5-AzadC
5-Azadeoxycytidine
5-Deoxyazacytidine
5AzadC
AzadC Compound
Dacogen
Decitabine Mesylate
NSC 127716
NSC-127716
Persistent link
https://www.medvik.cz/link/D000077209
Definition
An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA.
- DUI
- D000077209 MeSH Browser
- CUI
- M0062824
- History note
- 2019 (1977)
- Public note
- 2019; DECITABINE was indexed under AZACITIDINE 1981-2018, and under DEOXYCITIDNE 1977-1980
Allowable subheadings
- AD
- administration & dosage 3
- AE
- adverse effects 3
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics 1
- PD
- pharmacology 4
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 6
- TO
- toxicity
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
decitabine and cedazuridine drug combination Chemical MeSH Browser