Simendan [simendan]
- Terms
-
levosimendan
Simadax
-
((4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono)propanedinitrile
Dextrosimendan
Levosimendan
OR 1259
OR-1259
OR-1855
Simadax
A hydrazone and pyridazine derivative; the levo-form is a phosphodiesterase III inhibitor, calcium-sensitizing agent, and inotropic agent that is used in the treatment of HEART FAILURE.
- DUI
- D000077464 MeSH Browser
- CUI
- M0206272
- CAS
- Propanedinitrile, 2-(2-(4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazinylidene)-
- History note
- 2019 (1992)
- Public note
- 2019; SIMENDAN was indexed under HYDRAZONES and PYRIDAZINES 1992-2018
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 2
- AG
- agonists 0
- AA
- analogs & derivatives 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- EC
- economics 0
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 0
- PK
- pharmacokinetics 0
- PD
- pharmacology 2
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 5
- TO
- toxicity 0
- UR
- urine 0