Trabectedin [trabektedin]
topical
1
- Terms
-
ecteinascidin 743
trabectedin
Yondelis
-
Ecteinascidin 743
ET 743
ET-743
NSC 684766
Yondelis
Persistent link
https://www.medvik.cz/link/D000077606
Definition
A complex structure that includes isoquinolines joined by a cyclic ester; it is a DNA-binding agent and guanine N2 alkylator derived from the marine tunicate, Ecteinascidia turbinata. Trabectedin is used for the treatment of advanced soft-tissue SARCOMA, after failure of ANTHRACYCLINES or IFOSFAMIDE drug therapy.
- DUI
- D000077606 MeSH Browser
- CUI
- M0453081
- History note
- 2019 (1996)
- Public note
- 2019; TRABECTIDIN was indexed under DIOXOLES and TETRAHYDROISOQUINOLINES 2007-2018; and under ISOQUINOLINES 1996-2018
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology 1
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 1
- TO
- toxicity
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs