4-Amino-5-cyano-7-(D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidine. Antibiotic antimetabolite isolated from Streptomyces toyocaensis cultures. It is an analog of adenosine, blocks RNA synthesis and ribosome function, and is used mainly as a tool in biochemistry.

Annotation

an antineoplastic antibiotic & antimetabolite

DUI

D014127 MeSH Browser

CUI

M0021736

CAS

7H-Pyrrolo(2,3-d)pyrimidine-5-carbonitrile, 4-amino-7-beta-D-ribofuranosyl-

Previous indexing

Nucleosides (1966-1972); Ribonucleosides (1973-1974); Pyrroles (1966-1974); Nitriles (1966-1974); Pyrimidine Nucleosides (1974)

History note

91(75); was see under ANTIBIOTICS, AMINOGLYCOSIDE 1981-90; was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-80

Public note

91; was see under ANTIBIOTICS, AMINOGLYCOSIDE 1981-90; was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-80