Tirapazamine [tirapazamin]
topical
- Terms
-
3-amino-1,2,4-benzotriazin-1,4-dioxid
Tirazone
-
3-Amino-1,2,4-benzotriazine-1,4-dioxide
NSC 130181
SR 4233
SR-4233
Tirazone
WIN 59075
WIN-59075
Persistent link
https://www.medvik.cz/link/D000077704
Definition
A triazine derivative that introduces breaks into DNA strands in hypoxic cells, sensitizing tumor cells to the cytotoxic activity of other drugs and radiation.
- DUI
- D000077704 MeSH Browser
- CUI
- M0142901
- CAS
- 1,2,4-Benzotriazin-3-amine, 1,4-dioxide
- History note
- 2019 (1986)
- Public note
- 2019; TIRAPAZAMINE was indexed under TRIAZINES 1986-2018
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UR
- urine
...
Occurrences in Medvik records