Doripenem [doripenem]
- Terms
-
Doribax
-
2-(5-sulfamoylaminomethylpyrrolidin-3-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapen-2-em-3-carboxylic acid
S 4661
S-4661
A carbapenem derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIPENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of infections such as HOSPITAL-ACQUIRED PNEUMONIA, and complicated intra-abdominal or urinary-tract infections, including PYELONEPHRITIS.
- DUI
- D000077726 MeSH Browser
- CUI
- M0260551
- RN
- BHV525JOBH
- CAS
- 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-(((3S,5S)-5-(((aminosulfonyl)amino)methyl)-3-pyrrolidinyl)thio)-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-, (4R,5S,6S)-
- History note
- 2019 (1996)
- Public note
- 2019; DORIPENEM was indexed under CARBAPENEMS 1996-2018
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
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- analogs & derivatives 0
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- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
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- EC
- economics 0
- HI
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- IM
- immunology 0
- IP
- isolation & purification 0
- ME
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- PK
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- PD
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- PO
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- TU
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- TO
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- UR
- urine 0