Tolcapone [tolcapon]
topical
- Terms
-
Tasmar
tolkapon
-
3,4-Dihydroxy-5'-methyl-5-nitrobenzophenone
Ro 40-7592
Ro-40-7592
SOM0226
Tasmar
Persistent link
https://www.medvik.cz/link/D000077867
Definition
A benzophenone and nitrophenol compound that acts as an inhibitor of CATECHOL O-METHYLTRANSFERASE, an enzyme involved in the metabolism of DOPAMINE and LEVODOPA. It is used in the treatment of PARKINSON DISEASE in patients for whom levodopa is ineffective or contraindicated.
- DUI
- D000077867 MeSH Browser
- CUI
- M0182081
- CAS
- Methanone, (3,4-dihydroxy-5-nitrophenyl)(4-methylphenyl)-
- History note
- 2019 (1990)
- Public note
- 2019; TOLCAPONE was indexed under BENZOPHENONES and NITROPHENOLS 1990-2018
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D02.455.426.559.389.134.875
Tolcapone
D02.455.426.559.389.657.566.600
Niclofolan
D02.455.426.559.389.657.566.610
Nitrohydroxyiodophenylacetate
D02.455.426.559.389.657.566.620
Nitroxinil
D02.455.426.559.389.657.566.845
Tolcapone
D02.522.223.875
Tolcapone
D02.640.743.600
Niclofolan
D02.640.743.610
Nitrohydroxyiodophenylacetate
D02.640.743.620
Nitroxinil
D02.640.743.845
Tolcapone