Parthanatos [parthanatos]

topical
Terms

PARP-1-Dependent Cell Death
PARP-Dependent Cell Death

Persistent link   https://www.medvik.cz/link/D000079323
Definition

A type of regulated cell death initiated by hyperactivation of POLY (ADP-RIBOSE) POLYMERASE-1 (PARP-1) as a consequence of DNA DAMAGE; OXIDATIVE STRESS; HYPOXIA; HYPOGLYCEMIA; or INFLAMMATION. This leads to DNA FRAGMENTATION and CHROMATIN condensation.

DUI
D000079323 MeSH Browser
CUI
M000644242
Previous indexing
Cell Death (2008-2019)
History note
2020
Public note
2020

Allowable subheadings

DE
drug effects
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects

G Phenomena and Processes
G01 Physical Phenomena 77
G02 Chemical Phenomena 307
G03 Metabolic Phenomena obsolete
G03 Metabolism 1 197
G04 Cell Physiological Phenomena 515
G04.146 Cell Death 375
G04.146.954 Regulated Cell Death 5
G04.146.954.035 Apoptosis 2 061
G04.146.954.053 Autophagic Cell Death
G04.146.954.116 Disulfidptosis
G04.146.954.178 Ferroptosis 14
G04.146.954.285 Immunogenic Cell Death 8
G04.146.954.393 Mitochondrial Transmembrane Permeability-Driven Necrosis
G04.146.954.500 Necroptosis 15
G04.146.954.625 Paraptosis
G04.146.954.750 Parthanatos
G05 Genetic Phenomena 135
G06 Microbiological Phenomena 96
G07 Physiological Phenomena 176
G08 Reproductive and Urinary Physiological Phenomena 18
G09 Circulatory and Respiratory Physiological Phenomena 94
G10 Digestive System and Oral Physiological Phenomena 4
G11 Musculoskeletal and Neural Physiological Phenomena 17
G12 Immune System Phenomena 249
G13 Integumentary System Physiological Phenomena 14
G14 Ocular Physiological Phenomena 148
G15 Plant Physiological Phenomena 158
G16 Biological Phenomena 130
G17 Mathematical Concepts 66

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