Clonal Hematopoiesis [klonální hematopoéza]
- Terms
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CCUS
ICUS
idiopatické cytopenie nejasného významu
klonální cytopenie neurčitého významu
klonální hematopoéza neurčitého potenciálu
klonální hematopoéza neurčitého významu
klonální hematopoéza související s věkem
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Age-related Clonal Hematopoiesis
ARCH Age-related Clonal Hematopoiesis
CCUS Clonal Cytopenia of Undetermined Significance
CHIP Clonal Hematopoiesis of Indeterminate Potential
Clonal Cytopenia of Undetermined Significance
Clonal Hematopoiesis of Indeterminate Potential
ICUS Idiopathic Cytopenias of Undetermined Significance
Idiopathic Cytopenias of Undetermined Significance
Expansion of blood cells arising from mutant HEMATOPOIETIC STEM CELLS often related to aging. Mutations on epigenetic regulator genes are common in clonal hematopoiesis and may be a risk factor for HEMATOLOGIC NEOPLASMS and other cardiovascular diseases. When variant allele fraction is at least 2% and is present in the absence of severe cytopenias it is referred to as clonal hematopoiesis of indeterminate potential (CHIP).
- DUI
- D000082182 MeSH Browser
- CUI
- M000675997
- Previous indexing
- Hematopoiesis (1989-2020)
- History note
- 2021
- Public note
- 2021
Allowable subheadings