Gasdermins [gasderminy]

topical
1
Terms

Cancer Associated Gasdermin-Domain Containing (GSDMDC) Proteins

Persistent link   https://www.medvik.cz/link/D000094524
Definition

A family of pore-forming effector proteins that cause membrane permeabilization and PYROPTOSIS.. Gasdermin-induced pyroptosis plays a prominent role in many HEREDITARY DISEASES and autoinflammatory disorders as well as in CANCER.

DUI
D000094524 MeSH Browser
CUI
M000756051
History note
2023
Public note
2023

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 579
D12.776.157 Carrier Proteins 546
D12.776.157.530 Membrane Transport Proteins 207
D12.776.157.530.400 Ion Channels 276
D12.776.157.530.400.150 Calcium Channels 302
D12.776.157.530.400.163 Channelrhodopsins
D12.776.157.530.400.175 Chloride Channels 36
D12.776.157.530.400.337 Cyclic Nucleotide-Gated Cation Channels 52
D12.776.157.530.400.353 Gasdermins 1
D12.776.157.530.400.368 Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels 5
D12.776.157.530.400.400 Ligand-Gated Ion Channels 6
D12.776.157.530.400.500 Porins 21
D12.776.157.530.400.600 Potassium Channels 171
D12.776.157.530.400.875 Sodium Channels 94
D12.776.157.530.400.901 Transient Receptor Potential Channels 29
D12.776.157.530.400.950 Two-Pore Channels
D12.776.543 Membrane Proteins 850
D12.776.543.550 Membrane Glycoproteins 201
D12.776.543.550.450 Ion Channels 276
D12.776.543.550.450.150 Calcium Channels 302
D12.776.543.550.450.163 Channelrhodopsins
D12.776.543.550.450.175 Chloride Channels 36
D12.776.543.550.450.452 Cyclic Nucleotide-Gated Cation Channels 52
D12.776.543.550.450.464 Gasdermins 1
D12.776.543.550.450.476 Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels 5
D12.776.543.550.450.500 Ligand-Gated Ion Channels 6
D12.776.543.550.450.730 Porins 21
D12.776.543.550.450.750 Potassium Channels 171
D12.776.543.550.450.875 Sodium Channels 94
D12.776.543.550.450.937 Two-Pore Channels
D12.776.543.585 Membrane Transport Proteins 207
D12.776.543.585.400 Ion Channels 276
D12.776.543.585.400.150 Calcium Channels 302
D12.776.543.585.400.163 Channelrhodopsins
D12.776.543.585.400.175 Chloride Channels 36
D12.776.543.585.400.452 Cyclic Nucleotide-Gated Cation Channels 52
D12.776.543.585.400.464 Gasdermins 1
D12.776.543.585.400.476 Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels 5
D12.776.543.585.400.500 Ligand-Gated Ion Channels 6
D12.776.543.585.400.730 Porins 21
D12.776.543.585.400.750 Potassium Channels 171
D12.776.543.585.400.875 Sodium Channels 94
D12.776.543.585.400.901 Transient Receptor Potential Channels 29
D12.776.543.585.400.950 Two-Pore Channels

GSDMA protein, human Chemical MeSH Browser

GSDMB protein, human Chemical MeSH Browser

GSDMC protein, human Chemical MeSH Browser

GSDMD protein, human Chemical MeSH Browser

GSDME protein, human Chemical MeSH Browser

Gsdma protein, mouse Chemical MeSH Browser

Gsdma2 protein, mouse Chemical MeSH Browser

Gsdma3 protein, mouse Chemical MeSH Browser

Gsdmd protein, mouse Chemical MeSH Browser

Gsdmd protein, rat Chemical MeSH Browser

Gsdme protein, mouse Chemical MeSH Browser

Gsdme protein, rat Chemical MeSH Browser

PJVK protein, human Chemical MeSH Browser

gsdmeb protein, zebrafish Chemical MeSH Browser

pejvakin protein, mouse Chemical MeSH Browser

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