RNA, Guide, CRISPR-Cas Systems [vodící RNA, systémy CRISPR-Cas]
- Terms
-
CRISPR naváděcí RNA
crRNA
jednořetězcová naváděcí RNA
jednořetězcová řídící RNA
naváděcí RNA (systémy CRISPR-Cas)
navádějící RNA (systémy CRISPR-Cas)
řídící RNA, systémy CRISPR-Cas
sgRNA (single-guide RNA)
sgRNA (systémy CRISPR-Cas)
tracrRNA
transaktivační crRNA
-
CRISPR Guide RNA
CRISPR-Cas Systems sgRNA (Single Guide RNA)
crRNA
crRNA, Transactivating
Guide RNA (CRISPR-Cas Systems)
Guide RNA, CRISPR-Cas Systems
RNA, CRISPR Guide
RNA, Guide (CRISPR-Cas Systems)
RNA, Single Guide
RNA, Single-Guide
sgRNA (CRISPR-Cas Systems)
sgRNA (Single-Guide RNA)
Single Guide RNA
Single-Guide RNA
tracrRNA
Transactivating crRNA
A component of CRISPR-Cas SYSTEMS. Cas endodeoxyribonucleases assemble with a guide RNA complex, a hybrid of CRISPR RNA (crRNA) and transactivating crRNA (tracrRNA) molecules, to form an active complex that cleaves DNA. crRNA and tracrRNA can be synthetically fused into a single RNA molecule, namely single guide RNA. Synthetic sgRNA is used with CRISPR-Cas SYSTEMS for targeted GENE EDITING.
- Annotation
- do not confuse with RNA, GUIDE, KINETOPLASTIDA; do not confuse sgRNA (SINGLE-GUIDE RNA) with sgRNA (SUBGENOMIC RNA)
- DUI
- D000094704 MeSH Browser
- CUI
- M000756254
- Previous indexing
- CRISPR-Cas Systems (2014-2022); RNA, Guide, CRISPR-Cas Systems (2008-2022)
- History note
- 2023
- Public note
- 2023
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine