DNA Polymerase iota [DNA-polymerasa iota]
topical
- Terms
-
POL iota
POLiota
RAD30B
-
POL iota
POLiota
RAD30B
Persistent link
https://www.medvik.cz/link/D000094769
Definition
A highly error-prone DNA polymerase. It is a member of the Y-family of DNA polymerases that are DNA DAMAGE tolerant and involved in TRANSLESION DNA SYNTHESIS. DNA polymerase iota is an orthologue of yeast Rad30. Its replication fidelity is template dependent and favors Hoogsteen base-pairing at its active site.
- DUI
- D000094769 MeSH Browser
- CUI
- M0372410
- History note
- 2023 (2000)
- Public note
- 2023; was indexed as DNA-DIRECTED DNA POLYMERASE 2000-2022
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs
D08.811.913.696.445.308.300.876
Y-Family DNA Polymerases
D08.811.913.696.445.308.300.876.001
DNA Polymerase iota
POLI protein, human Chemical MeSH Browser