ProTides [ProTide technologie]
topical
1
- Terms
-
Pro-Tide
Pro-Tide přípravky
prodrug nukleotid
prodrug nukleotidy
proléčiva analogů nukleotidů
ProTide
ProTide proléčiva
-
Pro-Tide
Pro-Tides
Prodrug Nucleotide
Prodrug Nucleotides
ProTide
Persistent link
https://www.medvik.cz/link/D000095802
Definition
A class of prodrugs consisting of a 5'-nucleoside monophosphate in which the two hydroxyl groups are masked with an amino acid ester and an aryloxy component which once in the cell is enzymatically metabolized to deliver free 5'-monophosphate, and further transformed to the active 5'-triphosphate form of the nucleoside analogue.
- DUI
- D000095802 MeSH Browser
- CUI
- M000758863
- History note
- 2024
- Public note
- 2024
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AA
- analogs & derivatives
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
...
Occurrences in Medvik records
D
Chemicals and Drugs