DNA Damage Tolerance [tolerance poškození DNA]

topical
Terms

postreplikační oprava
postreplikační opravy
postreplikační reparace

 

DNA Damage Bypass Pathways
DNA Damage Tolerance Pathways
DNA Damage Tolerant Replication
Post Replication Repair
Post-Replication Repair
Postreplication Repair
Postreplicative Repair
Postreplicative Template Switching
Replication Fork Reversal
Replication Template Switching

Definition

Strategies that cells use to continue DNA replication when replicative DNA polymerases stall at DNA damage-blocked replication forks. These DNA damage tolerant replication mechanisms bypass the DNA DAMAGE, which may be repaired subsequently by various DNA REPAIR mechanisms.

DUI
D000097122 MeSH Browser
CUI
M000763247
History note
2024
Public note
2024

G Phenomena and Processes
G02.111.225 DNA Replication 287
G02.111.225.380 DNA Damage Tolerance
G02.111.225.380.500 Translesion DNA Synthesis
G02.111.225.760 DNA Replication Timing 3
G02.111.225.880 S Phase 81
G02.111.225.940 Telomere Shortening 35
G05.226 DNA Replication 287
G05.226.820 Endoreduplication 6
G05.226.880 S Phase 81
G05.226.940 Telomere Shortening 35