enzym UGT1A1 [UGT1A1 Enzyme]

tematický
Termíny

1-Naphthol UDP-Glucuronosyltransferase
Bilirubin Uridine-Diphosphoglucuronosyl Transferase 1A1
Phenol GCStransferase
Phenol UDP-Glucuronosyltransferase
UDP Glucuronosyltransferase 1A1
UDP-Glucuronosyltransferase 1A1
UGT1A1 Protein

Perzistentní odkaz   https://www.medvik.cz/link/D000099148
Definice

Glucuronosyltransferase encoded by UGT1 complex which encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini. It catalyzes reactions where lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility and excretion into either urine or bile. UGT1A1enzyme is essential for elimination and detoxification of drugs, xenobiotics and metabolites.

DUI
D000099148 MeSH Prohlížeč
CUI
M000768753
Historická pozn.
2026; UGT1A1 ENZYME was indexed under GLUCURONOSYLTRANSFERASE 2001-2026
Veřejná pozn.
2026 (2001)