Alkylating Agents [alkylační látky]
topical
91
- Terms
-
alkylační činidlo
alkylační látka
alkylující látka
alkylující látky
-
Alkylating Agent
Alkylator
Alkylators
Persistent link
https://www.medvik.cz/link/D000477
Definition
Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.
- DUI
- D000477 MeSH Browser
- CUI
- M0000721
- History note
- 66(64)
- Public note
- 66
Allowable subheadings
- AD
- administration & dosage 5
- AE
- adverse effects 7
- AN
- analysis 4
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis 1
- CH
- chemistry 2
- CL
- classification 2
- EC
- economics
- HI
- history 1
- IM
- immunology
- IP
- isolation & purification 1
- ME
- metabolism 2
- PK
- pharmacokinetics 1
- PD
- pharmacology 11
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 16
- TO
- toxicity 21
- UR
- urine 1
...
Occurrences in Medvik records
D
Chemicals and Drugs
D27.505.519.143
Amylin Receptor Agonists
D27.505.519.182
Antiglycation Agents
D27.505.519.241
Aversive Agents
D27.505.519.334
Cystine Depleting Agents
D27.505.519.952
Toll-Like Receptor Agonists
D27.505.519.957
Viral Fusion Protein Inhibitors