Anthramycin [anthramycin]
- Terms
-
Anthramycin, (11a alpha)-Isomer
Antramycin
A broad-spectrum spectrum antineoplastic antibiotic isolated from Streptomyces refuineus var. thermotolerans. It has low toxicity, some activity against Trichomonas and Endamoeba, and inhibits RNA and DNA synthesis. It binds irreversibly to DNA.
- DUI
- D000876 MeSH Browser
- CUI
- M0001309
- CAS
- 2-Propenamide, 3-(5,10,11,11a-tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1H-pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-, (11R-(2(E),11alpha,11abeta))-
- Previous indexing
- Benzodiazepinones (1974); Acrylamides (1973-1974); Pyrroles (1972-1974)
- History note
- 91(75); was see under BENZODIAZEPINONES 1975-90
- Public note
- 91; was see under BENZODIAZEPINONES 1975-90
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AA
- analogs & derivatives 1
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis 1
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 2
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UR
- urine
anthramycin-DNA Chemical MeSH Browser