Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.

DUI

D000894 MeSH Browser

CUI

M0001335

Previous indexing

Analgesics, Anti-Inflammatory (1966-1986); Anti-Inflammatory Agents (1966-1986)

History note

87; ANALGESICS, ANTI-INFLAMMATORY was heading 1975-89

Online note

use ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL to search ANALGESICS, ANTI-INFLAMMATORY 1975-89

Public note

87; ANALGESICS, ANTI-INFLAMMATORY was heading 1975-89