Toxic substances isolated from various strains of Streptomyces. They are 20-membered macrolides that inhibit oxidative phosphorylation and mitochondrial ATPases. Venturicidins A and B are glycosides. Used mainly as tools in the study of mitochondrial function.

Annotation

uncoupling agents & antifungal antibiotics; from Streptomyces

DUI

D014698 MeSH Browser

CUI

M0022603

Previous indexing

Glycosides (1973-1974); Antibiotics, Antifungal (1973-1976); Lactones (1973-1976); Rhamnose (1973-1974)

History note

91(77); was see under LACTONES 1977-90

Public note

91; was see under LACTONES 1977-90