Spironolactone [spironolakton]
- Terms
-
Aldactone
Spiro
Verospiron
-
Aldactone
Aldactone A
Aquareduct
Duraspiron
Espironolactona Alter
Espironolactona Mundogen
Flumach
Frumikal
Jenaspiron
Novo-Spiroton
Practon
SC-9420
Spiractin
Spiro L.U.T.
Spiro Von Ct
Spirobeta
Spirogamma
Spirolactone
Spirolang
Spirono-Isis
Spironone
Spirospare
Veroshpiron
Verospiron
Verospirone
A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
- DUI
- D013148 MeSH Browser
- CUI
- M0020352
- CAS
- Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, gamma-lactone, (7alpha,17alpha)-
Allowable subheadings
- AD
- administration & dosage 93
- AE
- adverse effects 55
- AG
- agonists
- AA
- analogs & derivatives 37
- AN
- analysis
- AI
- antagonists & inhibitors 3
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- EC
- economics
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 5
- PK
- pharmacokinetics 11
- PD
- pharmacology 61
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 181
- TO
- toxicity
- UR
- urine
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lasilacton Chemical MeSH Browser
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spiroprop Chemical MeSH Browser