(S-(E))-3,4,5,6,8,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione. One of a group of compounds known under the general designation of resorcylic acid lactones. Cis, trans, dextro and levo forms have been isolated from the fungus Gibberella zeae (formerly Fusarium graminearum). They have estrogenic activity, cause toxicity in livestock as feed contaminant, and have been used as anabolic or estrogen substitutes.

Annotation

a mycotoxin & non-steroidal estrogen; do not confuse with zearalanone (index under ZEARALENONE /analogs)

DUI

D015025 MeSH Browser

CUI

M0023120

CAS

1H-2-Benzoxacyclotetradecin-1,7(8H)-dione, 3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-, (S-(E))-

Previous indexing

Lactones (1966-1974); Resorcinols (1966-1974)

History note

91(75); was see under RESORCINOLS 1975-90

Public note

91; was see under RESORCINOLS 1975-90