A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.

DUI

D009118 MeSH Prohlížeč

CUI

M0014231

CAS

3(2H)-Isoxazolone, 5-(aminomethyl)-

Předchozí užití

Mycotoxins (1967-1978); Oxazoles (1966-1978); Toxins (1966)

Historická pozn.

86(79); was see under OXAZOLES 1979-85

Veřejná pozn.

86; was see under OXAZOLES 1979-85