A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.

DUI

D009118 MeSH Browser

CUI

M0014231

CAS

3(2H)-Isoxazolone, 5-(aminomethyl)-

Previous indexing

Toxins (1966); Mycotoxins (1967-1978); Oxazoles (1966-1978)

History note

86(79); was see under OXAZOLES 1979-85

Public note

86; was see under OXAZOLES 1979-85