A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of avidity, which refers to the strength of the antigen-antibody bond after formation of reversible complexes.

Annotation

do not confuse with BINDING SITES, ANTIBODY or ANTIGENIC DETERMINANTS

DUI

D000915 MeSH Browser

CUI

M0001362

Previous indexing

Antigenic Determinants (1970-1978); Binding Sites, Antibody (1973-1978); Antibodies (1966-1978); Antigen-Antibody Reactions (1966-1978)

History note

79

Public note

79