Antidepressive Agents, Tricyclic [antidepresiva tricyklická]
- Terms
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tricyklická antidepresiva
tricyklické antidepresivní léky
tricyklické antidepresivum
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Antidepressant Drugs, Tricyclic
Antidepressants, Tricyclic
Tricyclic Antidepressant
Tricyclic Antidepressant Drug
Tricyclic Antidepressive Agent
Tricyclic Antidepressive Agents
Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
- DUI
- D000929 MeSH Browser
- CUI
- M0001387
- Previous indexing
- Antidepressive Agents (1968-1974)
- History note
- 75
- Public note
- 75
Allowable subheadings
- AD
- administration & dosage 166
- AE
- adverse effects 131
- AN
- analysis 6
- BL
- blood 11
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 5
- CH
- chemistry 5
- CL
- classification 11
- EC
- economics 1
- HI
- history 1
- IM
- immunology 0
- IP
- isolation & purification 1
- ME
- metabolism 10
- PK
- pharmacokinetics 24
- PD
- pharmacology 113
- PO
- poisoning 9
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 245
- TO
- toxicity 15
- UR
- urine 1