Arachidonate 12-Lipoxygenase [arachidonát-12-lipoxygenasa]
- Terms
-
12-lipoxygenáza
arachidonát-12-lipoxygenáza
-
12-Lipoxygenase
Arachidonic Acid 12-Lipoxygenase
An enzyme that catalyzes the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-HPETE) which is itself rapidly converted by a peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-HETE). The 12-hydroperoxides are preferentially formed in PLATELETS.
- DUI
- D001092 MeSH Browser
- CUI
- M0001646
- CAS
- Arachidonate:oxygen 12-oxidoreductase
- Previous indexing
- Lipoxygenases (1974-1986); Oxygenases (1966-1973)
- History note
- 91(87); was see under ARACHIDONATE LIPOXYGENASES 1987-90
- Public note
- 91; was see under ARACHIDONATE LIPOXYGENASES 1987-90
Combination
- antagonists & inhibitors
- Lipoxygenase Inhibitors
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 1
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
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