An enzyme that catalyzes reversibly the transfer of a pyrophosphate group from ATP to the 3'-OH group of GDP or GTP with the formation of guanosine 3'-diphosphate 5'-diphosphate or guanosine 3'-diphosphate 5'-triphosphate and AMP. The enzyme, also called stringent factor, is located in the relA gene in stringent strains of bacteria. The above synthesis is induced by mRNA and uncharged tRNA which is bound to the aminoacyl-t-RNA binding site of the ribosome by a codon-specific association. EC 2.7.6.5.

DUI

D001277 MeSH Browser

CUI

M0001920

CAS

ATP:GTP 3'-pyrophosphotransferase

Previous indexing

Phosphotransferases (1966-1973); Adenosine Triphosphate (1966-1979); Bacterial Proteins (1966-1979); Guanine Nucleotides (1966-1979); Phosphotransferases, ATP (1974-1979); Pyrophosphates (1966-1979); Ribosomal Proteins (1975-1979)

History note

92; was ATP-GUANOSINE PHOSPHATE PYROPHOSPHOTRANSFERASE 1980-91 (see under PHOSPHOTRANSFERASES, ATP 1980-90)

Online note

use GTP PYROPHOSPHOKINASE to search ATP-GUANOSINE PHOSPHATE PYROPHOSPHOTRANSFERASE 1980-91

Public note

92; was ATP-GUANOSINE PHOSPHATE PYROPHOSPHOTRANSFERASE 1980-91 (see under PHOSPHOTRANSFERASES, ATP 1980-90)