Enzym, který katalyzuje reverzibilní přenos pyrofosfátové skupiny z ATP na 3'-OH skupinu GDP nebo GTP za vzniku guanosin-3',5'-difosfátu nebo guanosin-3'-difosfátu-5'-trifosfátu a AMP. Tento enzym, nazývaný také stringentní faktor, se nachází v genu relA u stringentních kmenů bakterií. Výše uvedená syntéza je indukována mRNA a nenabitou tRNA, která se váže kodonově specifickou vazbou na vazebné místo aminoacyl-t-RNA ribozomu. EC 2.7.6.5.

An enzyme that catalyzes reversibly the transfer of a pyrophosphate group from ATP to the 3'-OH group of GDP or GTP with the formation of guanosine 3'-diphosphate 5'-diphosphate or guanosine 3'-diphosphate 5'-triphosphate and AMP. The enzyme, also called stringent factor, is located in the relA gene in stringent strains of bacteria. The above synthesis is induced by mRNA and uncharged tRNA which is bound to the aminoacyl-t-RNA binding site of the ribosome by a codon-specific association. EC 2.7.6.5.

DUI

D001277 MeSH Prohlížeč

CUI

M0001920

CAS

ATP:GTP 3'-pyrophosphotransferase

Předchozí užití

Phosphotransferases (1966-1973); Adenosine Triphosphate (1966-1979); Bacterial Proteins (1966-1979); Guanine Nucleotides (1966-1979); Phosphotransferases, ATP (1974-1979); Pyrophosphates (1966-1979); Ribosomal Proteins (1975-1979)

Historická pozn.

92; was ATP-GUANOSINE PHOSPHATE PYROPHOSPHOTRANSFERASE 1980-91 (see under PHOSPHOTRANSFERASES, ATP 1980-90)

Online pozn.

use GTP PYROPHOSPHOKINASE to search ATP-GUANOSINE PHOSPHATE PYROPHOSPHOTRANSFERASE 1980-91

Veřejná pozn.

92; was ATP-GUANOSINE PHOSPHATE PYROPHOSPHOTRANSFERASE 1980-91 (see under PHOSPHOTRANSFERASES, ATP 1980-90)