Bicuculline [bikukulin]
topical
28
- Terms
-
6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)furo(3,4-e)1,3-benzodioxol-8(6H)one
Persistent link
https://www.medvik.cz/link/D001640
Definition
An isoquinoline alkaloid obtained from Dicentra cucullaria and other plants. It is a competitive antagonist for GABA-A receptors.
- DUI
- D001640 MeSH Browser
- CUI
- M0002466
- CAS
- Furo(3,4-e)-1,3-benzodioxol-8(6H)-one, 6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (R-(R*,S*))-
- Previous indexing
- Dioxoles (1972-1974); Alkaloids (1972-1974); Isoquinolines (1971-1974)
- History note
- 80(75); was see under ISOQUINOLINES 1975-79
- Public note
- 80; was see under ISOQUINOLINES 1975-79
Allowable subheadings
- AD
- administration & dosage 6
- AE
- adverse effects 3
- AG
- agonists 0
- AA
- analogs & derivatives 5
- AN
- analysis 0
- AI
- antagonists & inhibitors 3
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 1
- CL
- classification 0
- EC
- economics 0
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 1
- ME
- metabolism 2
- PK
- pharmacokinetics 0
- PD
- pharmacology 11
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 1
- TO
- toxicity 2
- UR
- urine 0
...
Occurrences in Medvik records