Carbidopa [karbidopa]
- Terms
-
karbidopa, R-izomer
karbidopa, S-izomer
methyldopahydrazin
-
Carbidopa, (R)-Isomer
Carbidopa, (S)-Isomer
Lodosin
Lodosyn
Methyldopahydrazine
MK-485
MK-486
An inhibitor of DOPA DECARBOXYLASE that prevents conversion of LEVODOPA to dopamine. It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA. It has no anti-parkinson activity by itself.
- DUI
- D002230 MeSH Browser
- CUI
- M0003345
- CAS
- Benzenepropanoic acid, alpha-hydrazino-3,4-dihydroxy-alpha-methyl-, monohydrate, (S)-
- Previous indexing
- Dopa (1972-1974); Hydrazines (1972-1974); Methyldopa (1972-1974)
- History note
- 80; was METHYLDOPAHYDRAZINE see under HYDRAZINES 1975-79; was METHYLDOPAHYDRAZINE 1973-74 (Prov)
- Online note
- use CARBIDOPA to search METHYLDOPAHYDRAZINE 1973-79 (as Prov 1973-74)
- Public note
- 80; was METHYLDOPAHYDRAZINE see under HYDRAZINES 1975-79
Allowable subheadings
- AD
- administration & dosage 15
- AE
- adverse effects 6
- AG
- agonists 0
- AA
- analogs & derivatives 1
- AN
- analysis 0
- AI
- antagonists & inhibitors 1
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 2
- CL
- classification 0
- EC
- economics 0
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 2
- ME
- metabolism 0
- PK
- pharmacokinetics 4
- PD
- pharmacology 7
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 20
- TO
- toxicity 0
- UR
- urine 0