Chloramphenicol [chloramfenikol]
- Terms
-
amfenikol
amfenikoly
-
Amphenicol
Amphenicols
Chlornitromycin
Chlorocid
Chloromycetin
Cloranfenicol
Detreomycin
Kloramfenikol
Levomycetin
Ophthochlor
Syntomycin
An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)
- Annotation
- an antibiotic
- DUI
- D002701 MeSH Browser
- CUI
- M0004121
- RN
- 66974FR9Q1
- CAS
- Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-, (R-(R*,R*))-
Allowable subheadings
- AD
- administration & dosage 63
- AE
- adverse effects 26
- AG
- agonists 0
- AA
- analogs & derivatives 7
- AN
- analysis 12
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 1
- BL
- blood 6
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 2
- CH
- chemistry 10
- CL
- classification 0
- EC
- economics 0
- HI
- history 0
- IM
- immunology 2
- IP
- isolation & purification 1
- ME
- metabolism 20
- PK
- pharmacokinetics 7
- PD
- pharmacology 83
- PO
- poisoning 0
- RE
- radiation effects 3
- ST
- standards 0
- SD
- supply & distribution 1
- TU
- therapeutic use 67
- TO
- toxicity 11
- UR
- urine 3