Serologic tests based on inactivation of complement by the antigen-antibody complex (stage 1). Binding of free complement can be visualized by addition of a second antigen-antibody system such as red cells and appropriate red cell antibody (hemolysin) requiring complement for its completion (stage 2). Failure of the red cells to lyse indicates that a specific antigen-antibody reaction has taken place in stage 1. If red cells lyse, free complement is present indicating no antigen-antibody reaction occurred in stage 1.

DUI

D003168 MeSH Browser

CUI

M0004919

History note

CONGLUTINATION REACTION was heading 1975-96 (see under COMPLEMENT FIXATION TESTS 1975-90); COMPLEMENT ABSORPTION TEST, CONGLUTINATING was see CONGLUTINATION REACTION 1992-96

Public note

CONGLUTINATION REACTION was heading 1975-96 (see under COMPLEMENT FIXATION TESTS 1975-90); COMPLEMENT ABSORPTION TEST, CONGLUTINATING was see CONGLUTINATION REACTION 1992-96